118994-93-7Relevant articles and documents
Kinetic resolution of 1,2-diols through highly site- and enantioselective catalytic silylation
Zhao, Yu,Mitra, Aurpon W.,Hoveyda, Amir H.,Snapper, Marc L.
, p. 8471 - 8474 (2008/09/18)
(Chemical Equation Presented) Resolved to silylate: A chiral silylation catalyst is used for kinetic resolution of three classes of acyclic 1,2-diols. The catalyst differentiates, with excellent precision, between the two hydroxy groups of a substrate. The majority of the diols, obtained in high enantiomeric purity, cannot be accessed with similar stereochemical purity through catalytic asymmetric dihydroxylation.
