Glyburide-d11, also known as Labelled Glyburide, is a second-generation sulfonylurea with hypoglycemic activity. It is a white solid and is used as an antidiabetic agent. Glyburide-d11 is a deuterated analog of Glyburide, which means it contains deuterium atoms instead of hydrogen atoms in its molecular structure. This deuteration makes it a useful internal standard for the quantification of Glyburide by gas chromatography (GC) or liquid chromatography (LC) mass spectrometry.
1189985-02-1
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Basic information
- Product Name: GLYBURIDE-D11
- Synonyms: GLYBURIDE-D11;5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide-d11, Adiab-d11, Azuglucon-d11, Bastiverit-d11, Glibenclamide-d11, Glidiabet-d11, Glimidstada-d11;1-[4-[2-(5-Chloro-2-MethoxybenzaMido)ethyl]phenylsulfonyl] -3-(cyclohexyl-d11)urea;5-Chloro-N-[2-[4-[[[(cyclohexylaMino-d11)carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide;Adiab-d11;Antibet-d11;Azuglucon-d11;Bastiverit-d11
- CAS NO:1189985-02-1
- Molecular Formula: C23H17ClD11N3O5S
- Molecular Weight: 505.071299558
- EINECS: N/A
- Product Categories: Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Isotope Labeled Compounds;Isotope Labelled Compounds
- Mol File: 1189985-02-1.mol
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Chemical Properties
- Melting Point: 240-242°C
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C Freezer
- Solubility: DMSO (Slightly), Methanol (Slightly)
- Stability: Hygroscopic
- CAS DataBase Reference: GLYBURIDE-D11(CAS DataBase Reference)
- NIST Chemistry Reference: GLYBURIDE-D11(1189985-02-1)
- EPA Substance Registry System: GLYBURIDE-D11(1189985-02-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1189985-02-1(Hazardous Substances Data)
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1189985-02-1 Usage
Uses
Used in Pharmaceutical Industry:Glyburide-d11 is used as an internal standard for the quantification of Glyburide by GCor LC-mass spectrometry. It helps in the accurate measurement and analysis of Glyburide levels in various pharmaceutical formulations, ensuring the quality and efficacy of antidiabetic drugs.
Used in Research and Development:
Glyburide-d11 is used as a research tool in the development of new antidiabetic drugs and therapies. Its deuterated nature allows researchers to study the metabolic pathways and pharmacokinetics of Glyburide, leading to a better understanding of its mechanism of action and potential side effects.
Used in Quality Control and Compliance:
Glyburide-d11 is used in quality control processes to ensure that pharmaceutical products containing Glyburide meet the required standards and regulations. It helps in the accurate quantification of Glyburide, ensuring that the dosage and purity of the drug are maintained within acceptable limits.
Used in Metabolism and Pharmacokinetics Studies:
Glyburide-d11 is used in metabolism and pharmacokinetics studies to investigate the absorption, distribution, metabolism, and excretion of Glyburide in the body. This information is crucial for optimizing the drug's dosage, administration, and overall effectiveness in managing diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 1189985-02-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,9,8 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1189985-02:
(9*1)+(8*1)+(7*8)+(6*9)+(5*9)+(4*8)+(3*5)+(2*0)+(1*2)=221
221 % 10 = 1
So 1189985-02-1 is a valid CAS Registry Number.
1189985-02-1Upstream product
1189985-02-1Downstream Products
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GLYBURIDE-D11
