1190069-82-9Relevant articles and documents
α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases
Orrling, Kristina M.,Marzahn, Melissa R.,Gutierrez-de-Teran, Hugo,Aqvist, Johan,Dunn, Ben M.,Larhed, Mats
experimental part, p. 5933 - 5949 (2009/12/24)
The impact of moving the P1 side-chain from the β-position to the α-position in norstatine-containing plasmepsin inhibitors was investigated, generating two new classes of tertiary alcohol-comprising α-benzylnorstatines and α-phenylnorstatines. Twelve α-s