119008-53-6 Usage
Uses
Used in Pharmaceutical Industry:
(2R,5R)-N-Benzyl-2,5-dimethylpyrrolidine is used as a key reagent for asymmetric syntheses in the pharmaceutical industry. Its ability to produce enantiomerically pure compounds is vital for the development of drugs with improved efficacy and reduced side effects, as the biological activity of chiral molecules can vary significantly between their enantiomers.
Used in Chemical Synthesis:
In the field of chemical synthesis, (2R,5R)-N-Benzyl-2,5-dimethylpyrrolidine is employed as a versatile building block for the creation of complex organic molecules. Its chiral nature enables the synthesis of a wide range of compounds with specific stereochemistry, which is crucial for various applications, including the development of new materials, catalysts, and biologically active molecules.
Used in Research and Development:
(2R,5R)-N-Benzyl-2,5-dimethylpyrrolidine is also utilized in research and development laboratories for the exploration of new synthetic methods and the study of stereoselective reactions. Its unique properties make it an invaluable tool for chemists working on the design and optimization of asymmetric catalysts and the development of novel enantioselective reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 119008-53-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,0,0 and 8 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 119008-53:
(8*1)+(7*1)+(6*9)+(5*0)+(4*0)+(3*8)+(2*5)+(1*3)=106
106 % 10 = 6
So 119008-53-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H19N/c1-11-8-9-12(2)14(11)10-13-6-4-3-5-7-13/h3-7,11-12H,8-10H2,1-2H3/t11-,12-/m1/s1
119008-53-6Relevant academic research and scientific papers
An evaluation of some hindered diamines as chiral modifiers of metal-promoted reactions
Illesinghe, Jayamini,Ebeling, Richard,Ferguson, Brett,Patel, Jim,Campi, Eva M.,Jackson, W. Roy,Robinson, Andrea J.
, p. 167 - 176 (2007/10/03)
Diamino analogues of the C2-symmetric chiral diphosphine ligands DuPHOS and BPE have been prepared and evaluated as chiral modifiers of the osmium tetraoxide dihydroxylation of stilbene. NMR experiments showed that these ligands were too bulky to coordinate to osmium. Less hindered analogues of these ligands were prepared and some were shown to act as ligands in dihydroxylation reactions but with poor enantioselectivity (e.e. 10%). The diamines have also been briefly evaluated as ligands in rhodium-catalyzed hydroformylation and copper-catalyzed phenolic coupling reactions. Once again, only low enantioselectivity was obtained.
