1190082-08-6Relevant articles and documents
A synthetic approach to ervatamine-silicine alkaloids. Enantioselective total synthesis of (-)-16-episilicine
Amat, Mercedes,Llor, Nuria,Checa, Begona,Molins, Elies,Bosch, Joan
experimental part, p. 178 - 189 (2010/04/04)
(Chemical Equation Presented) Starting from an appropriate unsaturated phenylglycinol-derived oxazolopiperidone lactam, the synthesis of (-)-16-episilicine is reported, the key steps being a stereoselective conjugate addition, a stereoselective alkylation, and a ring-closing metathesis reaction. This represents the first enantioselective total synthesis of an alkaloid of the silicine group. 2009 American Chemical Society.
An unexpected oxidation in the generation of cyclopenta[c]piperidines by ring-closing metathesis
Amat, Mercedes,Brunaccini, Elisa,Checa, Begona,Perez, Maria,Llor, Nuria,Bosch, Joan
scheme or table, p. 4370 - 4373 (2009/12/24)
Ring-closing metathesis reaction of dlenes A (n = 1, R= CO 2R′) leads to fused cyclopentenones C instead of the expected cyclopentene derivatives B. RCM reaction of the other dienes A takes place satisfactorily, affording the expected fused cyc
