1190085-90-5Relevant articles and documents
Guest-release control in enzyme-sensitive, amphiphilic-dendrimer-based nanoparticles through photochemical crosslinking
Raghupathi, Krishna R.,Azagarsamy, Malar A.,Thayumanavan
, p. 11752 - 11760 (2011)
Stimuli sensitive, facially amphiphilic dendrimers have been synthesized and their enzyme-responsive nature has been determined with dual fluorescence responses of both covalently conjugated and non-covalently bound reporter units. These dual responses ar
Role of Aromatic Interactions in Temperature-Sensitive Amphiphilic Supramolecular Assemblies
Munkhbat, Oyuntuya,Garzoni, Matteo,Raghupathi, Krishna R.,Pavan, Giovanni M.,Thayumanavan
, p. 2874 - 2881 (2016/04/19)
Aromatic interactions were found to greatly influence the temperature-dependent dynamic behavior within supramolecular assemblies. Using an amphiphilic dendron, we systematically changed the hydrophobic groups introducing increasing levels of aromaticity while keeping the hydrophilic part constant. We show that the supramolecular assemblies become less sensitive to temperature changes when aromatic interactions in the aggregate are increased. Conversely, the absence of aromaticity in the hydrophobic moieties produces temperature-sensitive aggregates. These results show that subtle molecular-level interactions can be utilized to control temperature-sensitive behavior in the nanoscale. These findings open up new design strategies to rationally tune the behavior of stimuli-responsive supramolecular assemblies on multiple spatiotemporal scales.
Photoregulated release of noncovalent guests from dendritic amphiphilic nanocontainers
Yesilyurt, Volkan,Ramireddy, Rajasekharreddy,Thayumanavan
scheme or table, p. 3038 - 3042 (2011/05/04)
Supramolecular disassembly: Phototriggered release of noncovalently sequestered lipophilic guest molecules from dendritic supramolecular assemblies has been demonstrated. Facially amphiphilic dendrimers have been shown to provide a unique opportunity to f
Enzyme-triggered disassembly of dendrimer-based amphiphilic nanocontainers
Azagarsamy, Malar A.,Sokkalingam, Punidha,Thayumanavan
supporting information; experimental part, p. 14184 - 14185 (2010/02/15)
(Figure Presented) We demonstrate a new enzyme-induced disassembly of amphiphilic nanocontainers based on dendrimers. Disassembly and the ensuing release of noncovalently bound guest molecules are of great interest because of their implications in areas s