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119011-56-2

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119011-56-2 Usage

Uses

7-Chloro-2-(methylsulfanyl)-[1,3]thiazolo[4,5-d]pyrimidine (cas# 119011-56-2) is used in the synthesis of 2,7-diamino-thiazolo[4,5-d]pyrimidine analogs as anti-tumor epidermal growth factor receptor tyrosine kinase inhibitors. It is also used in the preparation of thiazolopyrimidines and thienopyrimidines as antagonists of CCR2b receptors for the treatment of chemokine-mediated diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 119011-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,0,1 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 119011-56:
(8*1)+(7*1)+(6*9)+(5*0)+(4*1)+(3*1)+(2*5)+(1*6)=92
92 % 10 = 2
So 119011-56-2 is a valid CAS Registry Number.

119011-56-2Relevant articles and documents

NOVEL BICYCLIC HETEROCYCLIC COMPOUND

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, (2018/09/27)

Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

ANTI-INFLAMMATORY COMPOUND HAVING INHIBITORY ACTIVITY AGAINST MULTIPLE TYROSINE KINASES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

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, (2013/03/28)

The present invention is for the anti-inflammatory compounds that have an inhibitory activity against protein tyrosine kinases and their pharmaceutical composition(s) containing the compound as the active ingredient. Since the compounds of the present invention can inhibit multiple protein kinases associated with inflammatory diseases and immune disorders, they are useful for their prevention or treatment.

CHEMICAL COMPOUNDS

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Page/Page column 86-87, (2010/02/15)

The use of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein X1, X2, X3, X4, Ra, p, R1,Z,Y, R2, R3 and R4 are as d

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