119015-44-0

Basic information

• Product Name: Hexahydro-1H-isoindol-4(2H)-one
• Synonyms: Hexahydro-1H-isoindol-4(2H)-one;Octahydro-isoindol-4-one
• CAS NO: 119015-44-0
• Molecular Formula: C₈H₁₃NO
• Molecular Weight: 139.19492
• Mol File: 119015-44-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Hexahydro-1H-isoindol-4(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: Hexahydro-1H-isoindol-4(2H)-one(119015-44-0)
• EPA Substance Registry System: Hexahydro-1H-isoindol-4(2H)-one(119015-44-0)

Safety Data

• Hazardous Substances Data: 119015-44-0(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 130658-34-3 (3aR,7aS)-2-Trityl-octahydro-isoindol-4-one 

Downstream Products

• 130657-95-3 (3aS,4R,7aR)-4-(tert-Butoxycarbonyl-methyl-amino)-octahydro-isoindole-2-carboxylic acid benzyl ester 
• 130657-94-2 (3aR,4S,7aS)-4-tert-Butoxycarbonylamino-octahydro-isoindole-2-carboxylic acid benzyl ester 
• 130658-38-7 (3aS,4S,7aR)-4-Methanesulfonyloxy-octahydro-isoindole-2-carboxylic acid benzyl ester 
• 136562-52-2 1,3,3a,4,5,6-Hexahydro-isoindole-2-carboxylic acid benzyl ester 
• 130658-37-6 (3aS,4S,7aR)-4-Hydroxy-octahydro-isoindole-2-carboxylic acid benzyl ester 
• 130657-93-1 (3aS,4R,7aR)-4-Amino-octahydro-isoindole-2-carboxylic acid benzyl ester 
• 136562-51-1 (3aS,7aR)-4-Oxo-octahydro-isoindole-2-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis and antibacterial activity of new 7-(aminoazabicycloalkanyl)quinolonecarboxylic acids

A series of novel 7--6-fluoro-1-substituted quinolinecarboxylic acids (18-53) have been prepared and their antibacterial activities evaluated.These compounds are characterized structurally by a new amino-substituted azabicyclooctane, -nonane and -decane ring systems at the 7-position of quinolonecarboxylic acids.To compare the biological activities of enantiomers, (+)-7-octan-3-yl>-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolonecarboxylicacid hydrochloride (43, 44) were synthesized and evaluated for antibacterial activity.Compound 43 was more potent than 44 against both Gram-positive and Gram-negative organisms.The structure-activity relationships of these quinolonecarboxylic acids are also discussed. antibacterial activity / amino-substituted azabicycloalkane ring / substituted quinolonecarboxylic acids / structure-activity relationships