119018-06-3

Basic information

• Product Name: 4-(4-Methylbenzoyl)-2-thiophenesulfonamide
• Synonyms: 4-(4-Methylbenzoyl)-2-thiophenesulfonamide;4-(4-Methylbenzoyl)thiophene-2-sulfonamide
• CAS NO: 119018-06-3
• Molecular Formula: C₁₂H₁₁NO₃S₂
• Molecular Weight: 281.35
• Mol File: 119018-06-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 176 °C
• Boiling Point: 518.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.391±0.06 g/cm3(Predicted)
• PKA: 9.56±0.60(Predicted)
• CAS DataBase Reference: 4-(4-Methylbenzoyl)-2-thiophenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Methylbenzoyl)-2-thiophenesulfonamide(119018-06-3)
• EPA Substance Registry System: 4-(4-Methylbenzoyl)-2-thiophenesulfonamide(119018-06-3)

Safety Data

• Hazardous Substances Data: 119018-06-3(Hazardous Substances Data)

Upstream product

• 118993-67-2 4-(4-Methylbenzoyl)-thiophene-2-sulfonyl chloride 
• 118993-66-1 4-(4-methylbenzoyl)thiophene-2-sulfonic acid 
• 118993-65-0 (thiophen-3-yl)(p-tolyl)methanone 
• 104-85-8 para-methylbenzonitrile 

Relevant articles and documents

4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors

A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia

4-(benzoyl)thiophene(or furan)-sulfonamide and derivatives thereof for the topical treatment of elevated intraocular pressures

4-(benzoyl)thiophene(or furan)-2-sulfonamide and derivatives thereof are useful for the topical treatment of elevated intraocular pressure.