1190239-82-7Relevant academic research and scientific papers
Design, synthesis and docking studies of some spiro-oxindole dihydroquinazolinones as antibacterial agents
Zhang, Jin,Zhao, Jiawen,Wang, Liangpeng,Liu, Jia,Ren, Decheng,Ma, Yangmin
, p. 936 - 943 (2016)
Two series of spiro-oxindole dihydroquinazolinone derivatives have been designed and synthesized using a catalytic amount of nano cerium oxide with excellent product yields by a convenient one-pot process. The synthesized compounds were evaluated for thei
An environmental friendly approach for the synthesis of spiro[indoline-3',2-quinazoline]2',4(3H)-dione using 1-methylimidazolium hydrogen sulfate, as reusable catalyst
Kefayati, Hassan,Vazifeh, Masoumeh,Kazemi-Rad, Reyhaneh
, p. 1197 - 1201 (2014/04/03)
A facile and environmentally benign procedure for the synthesis of 3-aryl-1H-spiro[indoline-3',2-quinazoline] 2',4(3H)-dione from isatoic anhydride, aromatic amines and isatin derivatives in Bronsted acidic ionic liquid, 1-methylimidazoliumhydrogen sulfate, was reported. The ability to reuse the ionic liquid, the high yield, short reaction time and ease of purification are the important features of this process.
Ethylenediamine diacetate-catalyzed three-component reaction for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives
Narasimhulu, Manchala,Lee, Yong Rok
experimental part, p. 9627 - 9634 (2011/12/14)
Ethylenediamine diacetate (EDDA)-catalyzed one-pot syntheses of biologically interesting 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives from isatoic anhydride, amines, and benzaldehydes or isatins via a three-component condensation in aqueous media have been described. This method is of great value because of high yields and ease of handling.
