1190361-75-1Relevant academic research and scientific papers
5-Lipoxygenase-activating protein inhibitors: Development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl] -5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)
Hutchinson, John H.,Li, Yiwei,Arruda, Jeannie M.,Baccei, Christopher,Bain, Gretchen,Chapman, Charles,Correa, Lucia,Darlington, Janice,King, Christopher D.,Lee, Catherine,Lorrain, Dan,Prodanovich, Pat,Rong, Haojing,Santini, Angelina,Stock, Nicholas,Prasit, Peppi,Evans, Jilly F.
, p. 5803 - 5815 (2009)
The potent and selective 5-lipoxygenase-activating protein leukotriene synthesis inhibitor 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)- benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (11j) is described. Lead optimizati
