1190366-66-5Relevant academic research and scientific papers
DEPBT as coupling reagent to avoid racemization in a solution-phase synthesis of a kyotorphin derivative
Ramu, Vasanthakumar G.,Bardaji, Eduard,Heras, Montserrat
, p. 1481 - 1486 (2014/06/10)
The synthesis of IbKTP-NH2 with reduction of racemization up to no detectable level has been achieved using 3-(diethoxyphosphoryloxy)-1,2,3- benzotriazin-4(3H)-one (DEPBT). Among all coupling systems tested, only DEPBT-mediated amide bond formation between Nα-acylated tyrosine and arginine without loss of optical purity. Georg Thieme Verlag Stuttgart New York.
