1190372-37-2Relevant academic research and scientific papers
Synthesis and antimicrobial screening of 4H-2-berrcoyl-3-hydroxy-3-methyl- 2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one and 4H-3-methyl-2-phenyl furo[3,2-c]benzopyran-4-one
Mulwad,Hegde
experimental part, p. 128 - 133 (2009/12/04)
3-AcetyI-4-hydroxy-2H[l]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA to give 4H-2-benzoyl-3-hydroxy-3-methyl-2- phenyl 2,3-dihydro-furo[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HCI in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2- elimination. All compounds'have been screened for antimicrobial activity. They do not show significant activity.
