1190604-05-7

Upstream product

• 140-29-4 phenylacetonitrile 
• 69015-43-6 1-butyl-5-nitro-1H-benzo[d]imidazole 

Relevant academic research and scientific papers

Synthesis, Characterization, and DFT Calculations of New Fluorescent Cu(II) Complexes of Heterocyclic Ligands

The synthesis, spectral studies, and quantum chemical investigation of two new copper(II) complexes of fluorescent heterocyclic ligands derived from benzimidazole are reported. The fluorescent heterocyclic ligands are synthesized by the reduction of imida

New Zn(Ii) complexes derived from fluorescent benzimidazoles: Synthesis, spectral characterization, density functional theory calculations, and antibacterial studies

The synthesis, spectral characterization, quantum chemical investigations, and antibacterial activities of new Zn(II) complexes derived from fluorescent benzimidazoles are presented. Two fluorescent heterocyclic ligands were obtained from the reduction of

Interactions of human serum albumin with bioactive 3H-imidazo[4,5-a]acridines: Insights from fluorescence spectroscopic studies

Several 3H-imidazo[4,5-a]acridine derivatives were conveniently synthesized by the reaction of imidazo[4,5-a]acridones in boiling POCl3. The imidazoacridones were obtained by rearrangement of 3H-imidazo[4′,5′:3,4]benzo[c]isoxazoles in concentrated sulfuric acid containing nitrous acid at room temperature. The structures of all newly synthesized compounds were confirmed by IR, 1H NMR, and mass spectral data. The interactions of 3H-imidazo[4,5-a]acridines with human serum albumin (HSA) were studied by fluorescence spectroscopy. The binding of 3H-imidazo[4,5-a]acridines quenches the HSA fluorescence, revealing a 1: 1 interaction with a binding constant of about 2.34 × 105-3.16 × 106 M-1. A decrease in fluorescence intensity at 339 nm, when excited at 280 nm, is attributed to changes in the environment of the protein fluorophores caused by the presence of the ligand. The differences in interactions of 3H-imidazo[4,5-a]acridines with HSA were observed using spectrofluorimetry technique.

Synthesis, antiviral, and cytotoxic investigation of imidazo[4,5-a]acridones

The importance of virus infections and the early successes with some antiviral drugs have prompted the search for new agents, and it has been focused on compounds that are active against herpesviruses, retroviruses, and rhinoviruses. In this paper, 3H-imi

New fluorescent 3H-imidazo[4,5-e][2,1]benzoxazoles: Synthesis, spectroscopic characterization, and antibacterial activity

The new fluorophores of the 3H-imidazo[4,5-e][2,1]benzoxazoles series were synthesized by the regioselective nitration of 3-alkyl-8-phenyl-3H-imidazo[4,5-e][2,1]benzoxazoles. The latter compounds were obtained from the reaction of 1-alkyl-5-nitro-1H-benzi

Synthesis of imidazo[4,5-a]acridones and imidazo[4,5-a]acridines as potential antibacterial agents

New imidazo[4,5-a]acridone derivatives were synthesized from the rearrangement of 3H-imidazo[4′,5′:3,4]benzo[c]isoxazoles. New imidazo[4,5-a]acridines were obtained from the reaction of imidazo[4,5-a] acridones in boiling POCl3. All of these co