1190605-22-1Relevant academic research and scientific papers
Chemoenzymatic routes to polyoxygenated cyclooctenones related to the eastern hemisphere of the macrolactam tripartilactam
Vo, Yen,Banwell, Martin G.,Willis, Anthony C.
, p. 67 - 70 (2014)
Polyoxygenated cyclooctenones closely related to the enantiomeric form of the Eastern hemisphere of the structurally and biogenetically unusual macrolactam tripartilactam have been assembled from an enzymatically-derived and homochiral cis-1,2-dihydrocatechol. Key steps include the oxidative cleavage of the chlorinated double bond within a derivative of the starting cis-1,2-dihydrocatechol and a ring-closing metathesis reaction to establish the required eight-membered ring. Copyright
Chemoenzymatic access to versatile epoxyquinol synthons
Pinkerton, David M.,Banwell, Martin G.,Willis, Anthony C.
supporting information; experimental part, p. 4290 - 4293 (2009/12/26)
The enantiomerically pure and readily available metabolites 10-12 have been converted over four simple steps Into the epoxyquinol derivatives 22-24, respectively. Compounds 23 and 24 or their Immediate precursors have been exploited In efficient total syn
