1190614-95-9 Usage
Uses
Used in Pharmaceutical Industry:
(4S)-3-hex-5-ynoyl-4-benzyl-1,3-oxazolidin-2-one is used as a potential enzyme inhibitor for the development of new medications, targeting various diseases and conditions. Its ability to inhibit certain enzymes and biological processes makes it a promising candidate for further research and development in the pharmaceutical field.
Used in Antimicrobial Applications:
In the field of antimicrobials, (4S)-3-hex-5-ynoyl-4-benzyl-1,3-oxazolidin-2-one is used as a potential candidate for the development of new antibiotics. The presence of the oxazolidinone ring suggests that it may possess antimicrobial properties, which could be harnessed to combat bacterial infections.
Used in Organic Synthesis:
(4S)-3-hex-5-ynoyl-4-benzyl-1,3-oxazolidin-2-one is used as a building block in organic synthesis for the creation of more complex organic molecules. The presence of the benzyl group indicates its potential for use in the synthesis of a variety of compounds, which could have applications in various industries, including pharmaceuticals, materials science, and chemical research.
Further research and exploration of the properties and potential applications of (4S)-3-hex-5-ynoyl-4-benzyl-1,3-oxazolidin-2-one are necessary to fully understand its capabilities and maximize its utility in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1190614-95-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,6,1 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1190614-95:
(9*1)+(8*1)+(7*9)+(6*0)+(5*6)+(4*1)+(3*4)+(2*9)+(1*5)=149
149 % 10 = 9
So 1190614-95-9 is a valid CAS Registry Number.
1190614-95-9Relevant academic research and scientific papers
Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder
Moyes, Christopher R.,Berger, Richard,Goble, Stephen D.,Harper, Bart,Shen, Dong-Ming,Wang, Liping,Bansal, Alka,Brown, Patricia N.,Chen, Airu S.,Dingley, Karen H.,Di Salvo, Jerry,Fitzmaurice, Aileen,Gichuru, Loise N.,Hurley, Amanda L.,Jochnowitz, Nina,Miller, Randall R.,Mistry, Shruty,Nagabukuro, Hiroshi,Salituro, Gino M.,Sanfiz, Anthony,Stevenson, Andra S.,Villa, Katherine,Zamlynny, Beata,Struthers, Mary,Weber, Ann E.,Edmondson, Scott D.
, p. 1437 - 1453 (2014/03/21)
A series of conformationally restricted acetanilides were synthesized and evaluated as β3-adrenergic receptor agonists (β3-AR) for the treatment of overactive bladder (OAB). Optimization studies identified a five-membered ring as the preferred conformational lock of the acetanilide. Further optimization of both the aromatic and thiazole regions led to compounds such as 19 and 29, which have a good balance of potency and selectivity. These compounds have significantly reduced intrinsic clearance compared to our initial series of pyridylethanolamine β3-AR agonists and thus have improved unbound drug exposures. Both analogues demonstrated dose dependent β3-AR mediated responses in a rat bladder hyperactivity model.
HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS
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, (2009/10/30)
The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
