1190693-46-9Relevant academic research and scientific papers
Remote ether groups-directed regioselective and chemoselective cycloaddition of azides and alkynes
Duan, Xuelun,Zheng, Nan,Li, Ming,Sun, Xinhao,Lin, Zhuye,Qiu, Pan,Song, Wangze
, p. 4019 - 4023 (2021)
Remote ether groups could be used as directing groups to prepare fully substituted 5-ether-1,2,3-triazoles with exclusive 1,5-regioselectivities and excellent chemoselectivities. Ether group could coordinate with iridium catalyst by lone-pair electron at a distance (up to four σ bonds) away from alkyne to control the regioselectivity by weak coordination effect. The cycloaddition reaction chemoselectively occurred at the propargyl ether moiety of diyne to give unique fully substituted 4-alkynyl-triazole.
A direct route to triazole boronic esters and their application in the synthesis of small molecule arrays
Huang, Jianhui,Macdonald, Simon J.F.,Cooper, Anthony W.J.,Fisher, Gail,Harrity, Joseph P.A.
scheme or table, p. 5539 - 5541 (2010/01/18)
Alkynylboronates represent useful substrates for the direct synthesis of triazole boronic esters by their thermal cycloaddition with azides. A telescoped cycloaddition-cross-coupling protocol is reported and its employment in the synthesis of a small tria
