1190841-62-3Relevant academic research and scientific papers
Design and optimisation of potent gp120-CD4 inhibitors
Tran, Thien-Duc,Adam, Fiona M.,Calo, Frederick,Fenwick, David R.,Fok-Seang, Juin,Gardner, Iain,Hay, Duncan A.,Perros, Manos,Rawal, Jaiessh,Middleton, Donald S.,Parkinson, Tanya,Pickford, Christopher,Platts, Michelle,Randall, Amy,Stephenson, Peter T.,Vuong, Hannah,Williams, David H.
scheme or table, p. 5250 - 5255 (2010/03/24)
The synthesis and structure-activity relationship of a series of novel gp120-CD4 inhibitors are described. Pharmacokinetic studies and antiviral spectrum assessment of lead compounds led to the identification of compound 36, a potent gp120-CD4 inhibitor w
