119086-92-9

Upstream product

• 104698-13-7 silver salt of 2-[(3S,4R)-3-[(1'R)-1-allyloxycarbonyloxyethyl]-4-mercapto-2-oxo-azetidin-1-yl]-2-triphenylphosphoranylideneacetic acid allyl ester 
• 26189-59-3 1-chloro-1-(dimethylamino)-2-methyl-1-propene 

Relevant academic research and scientific papers

Bicyclic beta-lactam carboxylic acids

Compounds of the formula STR1 in which R1 is lower alkyl substituted by hydroxy or by protected hydroxy, R2 represents carboxy or functionally modified carboxy, R3 is hydrogen, amino, mono- or di-substituted amino, carbamoyl, hydroxy, protected hydroxy, carbamoyloxy, lower alkoxy, halogen, lower alkanoyl, sulphamoyl or heteroarylthio, each of R4 and R5, independently of the other, represents hydrogen, lower alkyl, hydroxy, protected hydroxy, lower alkoxy, halogen, amino, protected amino, lower alkanoylamino or carbamoyl, or R4 and R5 together represent methylenedioxy, Y represents a group of the formula --O--, --S-- or --NR6 --, R6 is hydrogen or lower alkyl, A1 represents lower alkylene or unsubstituted or substituted phenylene and A2 represents a direct bond or lower alkylene, and salts of such compounds, have antibacterial activity. The compounds of the formula I are manufactured by processes that are known per se.