1190877-41-8Relevant articles and documents
Design and discovery of 1,3-benzodiazepines as novel dopamine antagonists
Zhu, Zhaoning,Sun, Zhong-Yue,Ye, Yuanzan,McKittrick, Brian,Greenlee, William,Czarniecki, Michael,Fawzi, Ahmad,Zhang, Hongtao,Lachowicz, Jean E.
scheme or table, p. 5218 - 5221 (2010/03/24)
A series of novel 1,3-benzodiazapine based D1 antagonists was designed according to the understanding of pharmacophore models derived from SCH 23390 (1b), a potent and selective D1 antagonist. The new design features an achiral cyclic-amidine that maintai