1190882-64-4Relevant academic research and scientific papers
Convenient synthesis of allenylphosphoryl compounds: Via Cu-catalysed couplings of P(O)H compounds with propargyl acetates
Shen, Ruwei,Luo, Bing,Yang, Jianlin,Zhang, Lixiong,Han, Li-Biao
, p. 6451 - 6454 (2016/05/24)
A novel Cu-catalysed substitution reaction of propargyl acetates with P(O)H compounds is developed to afford allenylphosphoryl compounds via C-P bond coupling in high yields under mild conditions. A plausible mechanism involving the nucleophilic interception of the Cu-allenylidene intermediates is proposed.
Palladium(II)-Catalyzed Regio- and Stereoselective Hydroarylation of Diphenylphosphorylallenes with Arylboronic Acids in the Presence of Sodium Hydroxide and Oxygen
Chen, Yang,Ma, Dong-Mei,Ba, Fei-Fei,Sun, Jing,Liu, Tian,Zhu, Lei,Zhou, Ming-Dong
supporting information, p. 2849 - 2854 (2016/09/13)
The palladium(II)-catalyzed hydroarylation of diphenylphosphorylallenes (via 1,2-addition of the allenic double bond) with arylboronic acids in the presence of sodium hydroxide and oxygen is developed. The regioselectivities turn out to be well controlled, affording 2-aryl-3-(diphenylphosphinyl)alkenes as the only product. Moreover, the stereoselectivities for reactions of γ-substituted allenes can also be nicely controlled, resulting in the formation of Z-alkenes. The reaction shows high substituent loading capability and tolerance of various substituents. A mechanism, including transmetalation of arylboronic acid with palladium halides, insertion of the 1,2-allenic double bond to the Pd?Ar bond, and protonation to afford the final hydroarylation product is proposed. (Figure presented.).
Studies on highly regio- and stereoselective fluorohydroxylation reaction of 3-aryl-1,2-allenyl phosphine oxides with Selectfluor
He, Guangke,Fu, Chunling,Ma, Shengming
experimental part, p. 8035 - 8042 (2009/12/03)
The fluorohydroxylation of allenyl phosphine oxides with Selectfluor in commercial MeCN without prior treatment or a mixed solvent of anhydrous MeCN (refluxed over CaH2 and distilled before use) and 7.0 equiv of H2O or MeNO2/su
