1190955-18-0Relevant academic research and scientific papers
Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives
Wang, Tao,Kadow, John F.,Zhang, Zhongxing,Yin, Zhiwei,Gao, Qi,Wu, Dedong,Parker, Dawn DiGiugno,Yang, Zheng,Zadjura, Lisa,Robinson, Brett A.,Gong, Yi-Fei,Blair, Wade S.,Shi, Pei-Yong,Yamanaka, Gregory,Lin, Pin-Fang,Meanwell, Nicholas A.
scheme or table, p. 5140 - 5145 (2010/03/31)
4-Fluoro- and 4-methoxy-1-(4-benzoylpiperazin-1-yl)-2-(1H-indol-3-yl)ethane-1,2-dione (2 and 3, respectively) have been characterized as potent inhibitors of HIV-1 attachment that interfere with the interaction of viral gp120 with the host cell receptor C
