1190969-76-6 Usage
General Description
3-cyclopropylpyrazin-2-amine is a chemical compound with the molecular formula C7H9N3. It is a heterocyclic amine, containing a cyclopropyl ring and a pyrazine ring in its structure. This chemical is an amine, meaning it contains a nitrogen atom with a lone pair of electrons, making it a potential base. It is used as a building block in organic synthesis, and its derivatives have been investigated for potential pharmacological applications. Due to its unique structure and potential reactivity, 3-cyclopropylpyrazin-2-amine is of interest to researchers in the fields of organic chemistry and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1190969-76-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,0,9,6 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1190969-76:
(9*1)+(8*1)+(7*9)+(6*0)+(5*9)+(4*6)+(3*9)+(2*7)+(1*6)=196
196 % 10 = 6
So 1190969-76-6 is a valid CAS Registry Number.
1190969-76-6Relevant articles and documents
Imidazo-pyrazine derivatives as potent CXCR3 antagonists
Du, Xiaohui,Gustin, Darin J.,Chen, Xiaoqi,Duquette, Jason,McGee, Lawrence R.,Wang, Zhulun,Ebsworth, Karen,Henne, Kirk,Lemon, Bryan,Ma, Ji,Miao, Shichang,Sabalan, Emmanuel,Sullivan, Timothy J.,Tonn, George,Collins, Tassie L.,Medina, Julio C.
scheme or table, p. 5200 - 5204 (2010/03/24)
A general way of improving the potency of CXCR3 antagonists with fused hetero-bicyclic cores was identified. Optimization efforts led to the discovery of a series of imidazo-pyrazine derivatives with improved pharmacokinetic properties in addition to increased potency. The efficacy of the lead compound 21 is evaluated in a mouse lung inflammation model.