119098-03-2

Basic information

• Product Name: (Z)-ethyl 2-(7-benzyloxy-3-methyl-1-phenylsulphonyl-1H-indol-4-yl)-3-chloropropenoate
• CAS NO: 119098-03-2
• Molecular Weight: 510.01
• Mol File: 119098-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-ethyl 2-(7-benzyloxy-3-methyl-1-phenylsulphonyl-1H-indol-4-yl)-3-chloropropenoate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl 2-(7-benzyloxy-3-methyl-1-phenylsulphonyl-1H-indol-4-yl)-3-chloropropenoate(119098-03-2)
• EPA Substance Registry System: (Z)-ethyl 2-(7-benzyloxy-3-methyl-1-phenylsulphonyl-1H-indol-4-yl)-3-chloropropenoate(119098-03-2)

Safety Data

• Hazardous Substances Data: 119098-03-2(Hazardous Substances Data)

Upstream product

• 105805-20-7 7-benzyloxy-4-bromo-3-methyl-1-phenylsulphonyl-1H-indole 
• 105805-18-3 1-azido-2-(5'-benzyloxy-2'-bromophenyl)propan-2-ol 
• 119098-01-0 1-azido-2-(5'-benzyloxy-2'-bromophenyl)propene 
• 105805-17-2 2-(5'-benzyloxy-2'-bromophenyl)-2-methyl-oxirane 
• 105805-16-1 1-[2-bromo-5-(phenylmethoxy)phenyl]ethanone 
• 100-44-7 benzyl chloride 
• 121-71-1 3-Hydroxyacetophenone 
• 34068-01-4 1-[3-(phenylmethoxy)phenyl]ethan-1-one 
• 105805-21-8 ethyl (7-benzyloxy-3-methyl-1-phenylsulphonyl-1H-indol-4-yl)glyoxolate 
• 29949-92-6 (chloromethylene)triphenylphosphorane 

Relevant articles and documents

Formal Synthesis of the Antitumour Antibiotic CC-1065

A formal total synthesis of the potent antitumour antibiotic CC-1065 (1) is described; both the cyclopropapyrroloindole (2) and the 'dimeric' pyrroloindole (3) are synthesized by routes involving vinyl azide chemistry.The cyclopropapyrroloindole (2) is prepared from 5-benzyloxy-2-bromoacetophenone (Schemes 3-5), the key steps being the formation of both indoles by decomposition of the azides (9) and (13).The dimer (3) is prepared by coupling the monomeric pyrroloindoles (25) and (27), followed by functional group transformations (Scheme 7).