119102-91-9 Usage
Molecular structure
1-Benzyl-4-ethoxycarbonyl-1-azonia-bicyclo[2.2.1]heptane; bromide has a complex molecular structure, featuring a quaternary ammonium salt with a benzyl group and an ethoxycarbonyl group attached to a bicyclic nitrogen-containing ring.
Counterion
The bromide ion (Br-) serves as the counterion in the compound, balancing the positive charge of the quaternary ammonium salt.
Type of compound
It is a quaternary ammonium salt, which is a type of onium salt containing a positively charged nitrogen atom.
Functional groups
The compound contains a benzyl group (a phenyl group attached to a methyl group) and an ethoxycarbonyl group (an ester functional group with an ethoxy chain).
Bicyclic structure
The compound features a bicyclic nitrogen-containing ring, which is a key aspect of its unique properties and reactivity.
Applications
1-Benzyl-4-ethoxycarbonyl-1-azonia-bicyclo[2.2.1]heptane; bromide is often used as a reactant in organic synthesis and has potential applications in pharmaceuticals and medicinal chemistry.
Value in research
The compound's unique structure and properties make it valuable for creating various types of organic compounds and studying biological interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 119102-91-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,1,0 and 2 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 119102-91:
(8*1)+(7*1)+(6*9)+(5*1)+(4*0)+(3*2)+(2*9)+(1*1)=99
99 % 10 = 9
So 119102-91-9 is a valid CAS Registry Number.
119102-91-9Relevant academic research and scientific papers
Comparison of Azabicyclic Esters and Oxadiazoles as Ligands for the Muscarinic Receptor
Orlek, Barry S.,Blaney, Frank E.,Brown, Frank,Clark, Michael S. G.,Hadley, Michael S.,et al.
, p. 2726 - 2735 (2007/10/02)
The link between the cognitive deficit associated with Alzheimer type dementia and the loss of cholinergic function in the disease provides a basis for examining muscarinic agonists as potential therapeutic agents.This paper describes the design and synthesis of novel azabicyclic methyl esters as ligands for the muscarinic receptor.Replacement of the methyl ester by a 3-methyl-1,2,4-oxadiazole ring produces potent metabolically more stable muscarinic agonists capable of penetrating the central nervous system.These compounds generally show improved affinity relativeto the corresponding methyl esters. 3-Methyl-1,2,4-oxadiazole 7b has an affinity 4 times that of acetylcholine.Receptor affinity is discussed in relation to the size and geometry of the azabicyclic ring and the electronic properties of the heteroaromatic ring.
Synthesis of ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate
Orlek,Wadsworth,Wyman,King
, p. 1245 - 1246 (2007/10/02)
The dipolar cycloaddition reaction of α-methylene butyrolactone and N-benzyl azomethine ylid (5) affords the spirolactone (2) which rearranges to give ethyl 1-azabicyclo[2.2.1]hept-4-yl carboxylate (1) in excellent overall yield.
