1191052-84-2Relevant academic research and scientific papers
Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics
Cosner, Casey C.,Markiewicz, John T.,Bourbon, Pauline,Mariani, Christopher J.,Wiest, Olaf,Rujoi, Madalina,Rosenbaum, Anton I.,Huang, Amy Y.,Maxfield, Frederick R.,Helquist, Paul
supporting information; experimental part, p. 6494 - 6498 (2010/03/31)
A five-step synthesis of an array of N-aryl-3-alkylidenepyrrolinones, which are potential Niemann-Pick type C (NPC) disease therapeutics, is described. The synthetic route allows for the production of analogues, including photoaffinity and biotinylated de
