1191091-31-2

Basic information

• Product Name: 3-(1H-imidazol-1-yl)-N-(4-nitrophenyl)propanamide
• Synonyms: 3-(1H-imidazol-1-yl)-N-(4-nitrophenyl)propanamide
• CAS NO: 1191091-31-2
• Molecular Weight: 260.252
• Mol File: 1191091-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(1H-imidazol-1-yl)-N-(4-nitrophenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1H-imidazol-1-yl)-N-(4-nitrophenyl)propanamide(1191091-31-2)
• EPA Substance Registry System: 3-(1H-imidazol-1-yl)-N-(4-nitrophenyl)propanamide(1191091-31-2)

Safety Data

• Hazardous Substances Data: 1191091-31-2(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 19313-88-3 3-chloro-N-(4-nitrophenyl)propanamide 

Downstream Products

• 953900-09-9 N-(4-aminophenyl)-3-(1H-imidazol-1-yl)propanamide 

Relevant articles and documents

Design, synthesis and evaluation of 4,5-di-substituted acridone ligands with high G-quadruplex affinity and selectivity, together with low toxicity to normal cells

A series of 4,5-di-substituted acridones have been designed and synthesized. Several compounds show high affinity for telomeric G-quadruplex DNA in classical and competition FRET assays, together with low duplex DNA affinity, although they do not show activity in a telomerase assay or evidence of telomere shortening. They have low toxicity against a panel of cancer cell lines and a normal human fibroblast line, and produce potent senescence-based long-term growth arrest in the MCF7 and A549 cancer cell lines.