1191124-82-9Relevant academic research and scientific papers
Efficient total synthesis of (-)-kaitocephalin
Hamada, Makoto,Shinada, Tetsuro,Ohfune, Yasufumi
, p. 4664 - 4667 (2009)
A highly dlastereoselectlve total synthesis of (-)-kaltocephalln, a novel antagonist of lonotroplc glutamate receptors, was accomplished In 12 steps starting from 5-substltuted proline ester via the aldol reaction with OBO-serlne aldehyde, (E)-selectlve α,β-dehydroamlno acid synthesis using a new HWE reagent, and catalytic hydrogenation.
