119119-24-3

Upstream product

• 119119-27-6 tert-Butyl-[(2E,4Z)-1-pentyl-6-(tetrahydro-pyran-2-yloxy)-hexa-2,4-dienyloxy]-diphenyl-silane 
• 119119-15-2 (E)-3-[(1S,2R,3R,4R)-3-(Tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-propenal 
• 119119-13-0 (E)-3-[(1S,2R,3R,4R)-3-(Tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-acrylic acid ethyl ester 
• 119119-26-5 tert-Butyl-diphenyl-(1-{(E)-2-[(1R,2S,3S,4S)-3-(tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-vinyl}-hexyloxy)-silane 
• 119119-25-4 (E)-1-[(1S,2R,3R,4R)-3-(Tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-oct-1-en-3-ol 
• 119119-14-1 (E)-3-[(1S,2R,3R,4R)-3-(Tetrahydro-pyran-2-yloxymethyl)-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl]-prop-2-en-1-ol 
• 119119-12-9 (E)-3-((1R,2S,3S,4S)-3-Hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)-acrylic acid ethyl ester 

Relevant academic research and scientific papers

A New Stereoselective Synthesis of (E,Z)-Conjugated Hydroxy-Dienes, Key Intermediates for the Synthesis of HETES

A general and highly stereoselective synthesis of (E,Z)-conjugated hydroxy-dienes is described and its synthetic utility is illustrated by the synthesis of precursors of (+/-)-LTA4 methyl ester and (+/-)-5-HETE respectively.