119138-74-8Relevant academic research and scientific papers
Selective Heteronuclear NOE Enhancements in Benzoheterocycles. Effect of Ring Size on Indirect Three-Spin Effects
Redondo, Jordi,Sanchez-Ferrando, Francisco,Valls, Montserrat,Virgili, Albert
, p. 511 - 517 (1988)
The 80 MHz 1H NMR and 20 MHz 13C NMR spectra of five 4-methylcoumarins, six 4-methyl-2(1H)-quinolones and nine 3-methylbenzofurans, including six new compounds, were fully assigned.Homonuclear 1H NOEs and selective heteronuclear 13C NOEs were measured after low-power pre-saturation of the methyl protons.Indirect, negative heteronuclear NOE enhancements were found in suitable three-spin systems of the 13C-1H- type, and their magnitude was found to be dependent on ring size.The first examples of indirect, heteronuclear NOE enhancements on non-protonated carbons are described.KEY WORDS Heteronuclear NOE Selective heteronuclear 13C NOE Indirect negative NOE 13C-1H- three-spin effects Coumarins 2(1H)-Quinolones Benzofurans.
