119153-10-5

Upstream product

• 119119-16-3 tert-Butyl-diphenyl-{(1R,2R,3R,4S)-3-[(E)-3-(tetrahydro-pyran-2-yloxy)-propenyl]-7-oxa-bicyclo[2.2.1]hept-5-en-2-ylmethoxy}-silane 
• 110-87-2 3,4-dihydro-2H-pyran 
• 119119-12-9 (E)-3-((1R,2S,3S,4S)-3-Hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-5-en-2-yl)-acrylic acid ethyl ester 

Relevant academic research and scientific papers

A New Stereoselective Synthesis of (E,Z)-Conjugated Hydroxy-Dienes, Key Intermediates for the Synthesis of HETES

A general and highly stereoselective synthesis of (E,Z)-conjugated hydroxy-dienes is described and its synthetic utility is illustrated by the synthesis of precursors of (+/-)-LTA4 methyl ester and (+/-)-5-HETE respectively.