1191885-45-6 Usage
Description
(R)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid is a chiral compound that features a piperazine ring with a carboxylic acid and a tert-butoxycarbonyl (Boc) protecting group. (R)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid is characterized by its (R) configuration, which denotes the absolute configuration of the asymmetric carbon atom. It is known for its potential applications in organic synthesis, especially in the formation of peptide bonds and as a building block in the synthesis of pharmaceutical compounds. The Boc protecting group is a common feature in this compound, serving to protect amines during chemical reactions, thus enabling selective reactions at other functional groups. The presence of the piperazine ring also suggests potential bioactivity, as piperazine derivatives are recognized for their pharmacological properties.
Uses
Used in Organic Synthesis:
(R)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid is used as a building block for the synthesis of complex organic molecules, particularly in the formation of peptide bonds. Its presence allows for the creation of diverse pharmaceutical compounds through selective reactions.
Used in Pharmaceutical Compounds:
In the Pharmaceutical Industry, (R)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid is used as a key intermediate in the development of new drugs. Its unique structure and the Boc protecting group facilitate the synthesis of bioactive molecules with potential therapeutic applications.
Used in Chemical Reactions with Selectivity:
(R)-1-(tert-Butoxycarbonyl)-5-oxopiperazine-2-carboxylic acid is utilized as a reactant in chemical reactions where selectivity is crucial. The Boc group protects the amine function, allowing for reactions to occur at other sites within the molecule without affecting the amine group. This selective protection is vital for the synthesis of complex organic compounds with specific desired properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1191885-45-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,1,8,8 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1191885-45:
(9*1)+(8*1)+(7*9)+(6*1)+(5*8)+(4*8)+(3*5)+(2*4)+(1*5)=186
186 % 10 = 6
So 1191885-45-6 is a valid CAS Registry Number.
1191885-45-6Relevant articles and documents
Synthesis of (S)- and (R)-5-oxo-piperazine-2-carboxylic acid and its application to peptidomimetics
Guitot, Karine,Carboni, Stefano,Reiser, Oliver,Piarulli, Umberto
experimental part, p. 8433 - 8436 (2010/01/16)
(Chemical Equation Presented) A straightforward synthesis of (S)- and (R)-N-Boc-5-oxopiperazine-2-carboxylic acid is reported starting from L- or D-serine and ethyl glyoxylate. Those were evaluated as constituents in two tetrapeptides by studying their se
