1191907-18-2Relevant academic research and scientific papers
Discovery of a novel class of isoxazoline voltage gated sodium channel blockers
Shao, Pengcheng P.,Ye, Feng,Weber, Ann E.,Li, Xiaohua,Lyons, Kathryn A.,Parsons, William H.,Garcia, Maria L.,Priest, Birgit T.,Smith, McHardy M.,Felix, John P.,Williams, Brande S.,Kaczorowski, Gregory J.,McGowan, Erin,Abbadie, Catherine,Martin, William J.,McMasters, Daniel R.,Gao, Ying-Duo
body text, p. 5329 - 5333 (2010/04/26)
Analogs of the previously reported voltage gated sodium channel blocker CDA54 were prepared in which one of the amide functions was replaced with aromatic and non-aromatic heterocycles. Replacement of the amide with an aromatic heterocycle resulted in sig
