1191933-76-2Relevant academic research and scientific papers
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors α/γ dual agonists with improved potency and reduced adverse effects on skeletal muscle function
Fracchiolla, Giuseppe,Laghezza, Antonio,Piemontese, Luca,Tortorella, Paolo,Mazza, Fernando,Montanari, Roberta,Pochetti, Giorgio,Lavecchia, Antonio,Novellino, Ettore,Pierno, Sabata,Camerino, Diana Conte,Loiodice, Fulvio
supporting information; experimental part, p. 6382 - 6393 (2010/03/31)
The preparation of a new series of 2-aryloxy-3-phenyl-propanoic acids, resulting from the introduction of a linker into the diphenyl system of the previously reported PPARα/γ dual agonist 1, allowed the identification of new ligands with improved potency
