1192025-01-6 Usage
Description
2-(3-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a chemical compound that is utilized in various applications across different industries. It is known for its unique properties that make it suitable for specific uses, such as in the design of low-temperature continuous flow chemistry platforms and as a reagent in the preparation of FASN inhibitors.
Uses
Used in Pharmaceutical Industry:
2-(3-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a reagent for the preparation of FASN inhibitors. These inhibitors are useful in the treatment of cancer and other diseases, as they help regulate the activity of the fatty acid synthase enzyme, which is often overexpressed in cancer cells.
Used in Chemical Research and Development:
In the field of chemical research and development, 2-(3-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used in the design and application of low-temperature continuous flow chemistry platforms for cryogenic reactions. These platforms are essential for conducting reactions at extremely low temperatures, which can lead to improved reaction yields and selectivity, as well as enhanced safety and efficiency in the laboratory.
Overall, 2-(3-Chloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile compound with applications in both the pharmaceutical industry and chemical research and development. Its unique properties make it a valuable asset in the development of new drugs and the advancement of chemical synthesis techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 1192025-01-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,2,0,2 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1192025-01:
(9*1)+(8*1)+(7*9)+(6*2)+(5*0)+(4*2)+(3*5)+(2*0)+(1*1)=116
116 % 10 = 6
So 1192025-01-6 is a valid CAS Registry Number.
1192025-01-6Relevant articles and documents
Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes
Kuleshova, Olena,Asako, Sobi,Ilies, Laurean
, p. 5968 - 5973 (2021/05/31)
A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug molecules such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand.
