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CAS

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1192063-83-4

tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1192063-83-4 Structure

  • Basic information

    1. Product Name: tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate
    2. Synonyms: tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate
    3. CAS NO:1192063-83-4
    4. Molecular Formula:
    5. Molecular Weight: 389.535
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1192063-83-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate(1192063-83-4)
    11. EPA Substance Registry System: tert-butyl 4-{(1R,2S)-2-[(2R)-3-(benzyloxy)-2-hydroxy-propyl]cyclopropyl}piperidine-1-carboxylate(1192063-83-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1192063-83-4(Hazardous Substances Data)

1192063-83-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1192063-83-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,2,0,6 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1192063-83:
(9*1)+(8*1)+(7*9)+(6*2)+(5*0)+(4*6)+(3*3)+(2*8)+(1*3)=144
144 % 10 = 4
So 1192063-83-4 is a valid CAS Registry Number.

1192063-83-4Relevant articles and documents

SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

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, (2011/02/24)

Substituted cyclopropyl compounds of the formula I: are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.

Design of potent and selective GPR119 agonists for type II diabetes

Szewczyk, Jason W.,Acton, John,Adams, Alan D.,Chicchi, Gary,Freeman, Stanley,Howard, Andrew D.,Huang, Yong,Li, Cai,Meinke, Peter T.,Mosely, Ralph,Murphy, Elizabeth,Samuel, Rachel,Santini, Conrad,Yang, Meng,Zhang, Yong,Zhao, Kake,Wood, Harold B.

, p. 2665 - 2669 (2011/06/20)

Screening of the Merck sample collection identified compound 1 as a weakly potent GPR119 agonist (hEC50 = 3600 nM). Dual termini optimization of 1 led to compound 36 having improved potency, selectivity, and formulation profile, however, modest

SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

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, (2009/12/02)

Substituted cyclopropyl compounds of formula (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.

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