1192110-04-5

Basic information

• Product Name: 1-(R)-(+)-tert-butylsulfinyl-2-(methoxymethoxy)benzene
• Synonyms: 1-(R)-(+)-tert-butylsulfinyl-2-(methoxymethoxy)benzene
• CAS NO: 1192110-04-5
• Molecular Weight: 242.339
• Mol File: 1192110-04-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(R)-(+)-tert-butylsulfinyl-2-(methoxymethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(R)-(+)-tert-butylsulfinyl-2-(methoxymethoxy)benzene(1192110-04-5)
• EPA Substance Registry System: 1-(R)-(+)-tert-butylsulfinyl-2-(methoxymethoxy)benzene(1192110-04-5)

Safety Data

• Hazardous Substances Data: 1192110-04-5(Hazardous Substances Data)

Upstream product

• 68314-54-5 1-bromo-2-(methoxymethoxy)benzene 
• 67734-35-4 (R)-tert-butyl tert-butanethiosulfinate 
• 95-56-7 2-hydroxybromobenzene 

Downstream Products

• 1192110-05-6 C₁₀H₁₄O₂S 

Relevant articles and documents

A study of enantioselective syntheses by Sharpless asymmetric oxidation for aryl sulfoxides containing oxygen groups at the ortho position

Abstract: While ortho-alkoxy aryl sulfoxides including various substituents were synthesized by Sharpless asymmetric oxidation reaction, we optimized the reaction conditions and screened better combination of starting materials to obtain high enantioselectivity. The result suggested new information that electron-withdrawing substituents on the aromatic ring have a strong influence upon enantioselectivity of the products. Also, several chiral ligands for Sharpless asymmetric oxidation reaction were evaluated to improve the enantioselectivity. Graphic abstract: High enantioselectivity of ortho-alkoxy aryl chiral sulfoxides have been achieved by Sharpless oxidation reaction using Ti(O-i-Pr)4 and diethyl tartrate under anhydrous condition. In particular, the enantioselctivity of products was influenced by electron-withdrawing substituents on the aromatic ring, such as nitro, ester and aldehyde groups.[Figure not available: see fulltext.]