1192123-45-7Relevant academic research and scientific papers
Enantioselective synthesis of the 3C-protease inhibitor (-)-thysanone by a Staunton-Weinreb annulation strategy
Sperry, Jonathan,Tsz, Ying Yuen,Brimble, Margaret A.
experimental part, p. 2561 - 2569 (2009/12/25)
The total synthesis of (-)-thysanone is described. The key step involves the addition of an o-toluate anion to a lactone to create the naphthopyran framework (Staunton-Weinreb annulation). This synthesis further confirms the absolute stereochemistry of th
