1192123-48-0Relevant articles and documents
Enantioselective synthesis of the 3C-protease inhibitor (-)-thysanone by a Staunton-Weinreb annulation strategy
Sperry, Jonathan,Tsz, Ying Yuen,Brimble, Margaret A.
, p. 2561 - 2569 (2009)
The total synthesis of (-)-thysanone is described. The key step involves the addition of an o-toluate anion to a lactone to create the naphthopyran framework (Staunton-Weinreb annulation). This synthesis further confirms the absolute stereochemistry of th
