119219-99-7Relevant academic research and scientific papers
A NEW METHOD FOR THE PREPARATION OF β-(ALKYLAMINO)-CARBONYL COMPOUNDS BY REARRANGEMENT OF β-CHLOROIMINES VIA AZETIDINE INTERMEDIATES
Sulmon, Paul,Kimpe, Norbert De,Schamp, Niceas
, p. 2937 - 2956 (2007/10/02)
The reaction of β-chloroimines with sodium methoxide in methanol gave rise to β-(alkylamino)- and β-(arylamino)-carbonyl compounds in high yield.The reaction mechanism for the generation of β-(alkylamino)- and β-(arylamino)-carbonyl compounds passes via a
SYNTHESIS OF AZETIDINES FROM β-CHLORO IMINES
Sulmon, Paul,Kimpe, Norbert De,Schamp, Niceas,Tinant, Bernard,Declercq, Jean-Paul
, p. 3653 - 3670 (2007/10/02)
The reaction of β-chloro imines 4 with potassium cyanide in methanol or with lithium aluminium hydride in dry ether gave rise to 2-cyanoazetidines 5 and azetidines 21.The reaction proceeded by nucleophilic addition of cyanide or hydride across the carbon-
