1192191-39-1Relevant academic research and scientific papers
An improved synthesis of N-aryl and N-heteroaryl substituted homopiperazines-from conventional thermal conditions to scaling-up using microwave heating
Sch?n, Uwe,Messinger, Josef,Buckendahl,Prabhu,Konda
experimental part, p. 8125 - 8131 (2009/12/26)
An efficient Pd(0)-catalyzed Buchwald-Hartwig protocol for the facile preparation of N-aryl and N-heteroaryl substituted homopiperazines is described. The syntheses proceeded with aryl- and heteroaryl halides in high yields using X-Phos as best ligand. Th
