1192216-82-2Relevant articles and documents
Stereocontrolled generation of the (2R) chroman core of vitamin E: Total synthesis of (2R,4'RS,8'RS)-α-tocopherol
Hernandez-Torres, Gloria,Urbano, Antonio,Carmen Carreno,Colobert, Francoise
supporting information; experimental part, p. 4930 - 4933 (2010/01/16)
(2R,4'RS,8'RS)-α-Tocopherol (1) was prepared using, as the two key steps, a novel diastereoselective TiCl4-promoted (S)-sulfoxide-directed allylation of ketal 2 with allyl trimethyl silane 3 to efficiently generate the challenging (2R) stereocenter of the