1192314-41-2Relevant academic research and scientific papers
Novel delta opioid receptor agonists exhibit differential stimulation of signaling pathways
Peng, Youyi,Zhang, Qiang,Arora, Sonia,Keenan, Susan M.,Kortagere, Sandhya,Wannemacher, Kenneth M.,Howells, Richard D.,Welsh, William J.
experimental part, p. 6442 - 6450 (2011/02/26)
A novel family of 1,3,5-trisubstituted 1,2,4-triazoles was discovered as potent and selective ligands for the δ opioid receptor by rational design. Compound 5b exhibited low-nanomolar in vitro binding affinity (IC50 = 5.8 nM), excellent selecti
