1192322-83-0Relevant academic research and scientific papers
Effect of ring fusion stereochemistry on double bond geometry. Unexpected formation of nine-membered cyclic ether with E-configurated double bond through RCM
Ghosh, Subrata,Hossain, Md. Firoj,Malik, Chanchal K.,Maity, Soumitra
experimental part, p. 9159 - 9164 (2011/01/12)
Formation of a nine-membered cyclic ether with E-configurated double bond was observed during construction of 5-9-5 tricycles through RCM of dienes. Ring fusion stereochemistry in the products oxonenes was found to have profound influence on the olefin geometry. cis-anti-cis 5-9-5 tricycle was obtained with Z-configurated olefin while cis-syn-cis 5-9-5 system was obtained with E- as well as Z-configurated double bond with the former predominating.
