119238-52-7

Usage

Uses

Used in Pharmaceutical Industry:
D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]is used as a therapeutic agent for its potential in treating conditions such as osteoarthritis, liver disease, and neurological disorders. Its antioxidant and anti-aging properties make it a promising candidate for the development of pharmaceutical products.
Used in Cosmetic Industry:
D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]is used as an ingredient in cosmetic products for its skin health benefits. It promotes wound healing and supports overall skin health, making it a valuable component in skincare formulations.
Used in Food Industry:
D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]is used as a nutritional supplement in the food industry, as it plays a crucial role in protein synthesis and is involved in the formation of collagen, cartilage, and other connective tissues. Its presence in foods such as meat, fish, and dairy products contributes to their nutritional value.
Used in Health and Wellness Applications:
D-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]is used as a dietary supplement for its health and wellness benefits. Its antioxidant properties and potential therapeutic effects make it a valuable addition to health and wellness products, promoting overall well-being and supporting the prevention and treatment of various conditions.

Upstream product

• 7440-66-6 zinc 
• 78825-16-8 1-(3-mercapto-2-D-methyl-1-oxopropyl)-L-proline 

Downstream Products

• 460-19-5 ethanedinitrile 
• 75479-46-8 (S)-1-[3-((R)-2-Amino-2-carboxy-ethyldisulfanyl)-2-methyl-propionyl]-pyrrolidine-2-carboxylic acid 
• 77083-33-1 (S)-1-{3-[1-(4-Dimethylamino-3,5-dinitro-phenyl)-2,5-dioxo-pyrrolidin-3-ylsulfanyl]-2-methyl-propionyl}-pyrrolidine-2-carboxylic acid 
• 128960-77-0 glutathione 
• 64838-57-9 captopril disulfide 
• 78636-30-3 captopril-glutathione mixed disulfide 
• 78636-29-0 (S)-1-(2-Methyl-3-methylsulfanyl-propionyl)-pyrrolidine-2-carboxylic acid 
• 78636-28-9 (S)-1-(3-Methanesulfinyl-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid 
• 77083-32-0 (S)-1-{3-[2-(4-Bromo-phenyl)-2-oxo-ethylsulfanyl]-2-methyl-propionyl}-pyrrolidine-2-carboxylic acid 
• 78636-31-4 C₁₄H₂₂N₂O₆S₂ 

Relevant academic research and scientific papers

Process for preparation of optically active N-mercaptoalkanoylamino acids

A process is disclosed wherein an optically active N-mercaptoalkanoylamino acid is prepared by (1) reacting an optically active β-hydroxyalkanoic acid, with a halogenating reagent to prepare an optically active β-haloalkanoyl halide (2) reacting the β-haloalkanoyl halide with an amino acid to produce an optically active N-β-haloalkanoylamino acid and (3) reacting the N-β-haloalkanoylamino acid with a reagent capable of converting the halogen into the thiol group, the configuration of the formulas (II), (III), (IV), (V), and (VI) being retained in all the optically active compounds throughout the process to prepare the compound represented by formula (I). The product of the present invention, for example, N-(3-mercapto-2-D-methylpropanoyl)-L-proline inhibits the enzymatic conversion of angiotensin I into angiotensin II and therefore is useful for relieving angiotensin-related hypertension.

Pyridinium salts

The invention concerns compounds of formula STR1 wherein the sulphur is bonded to the pyridinium ring at position 2 or 4, Y is --S-- or --CH2 --, R represents hydrogen, or a lower alkyl group, or other carboxylic protecting group; R1 represents hydrogen or lower alkyl; R2 represents lower alkyl, aryl of 6 to 10 carbon atoms or aralkyl of 7 to 11 carbon atoms; R3 represents hydrogen or a substituent selected from lower alkyl, halogen and lower alkoxy; q and r are each 1 or 2; and X? represents a halide ion or an organosulphonate ion, which are antihypertensive agents and are useful as intermediates to captopril and analogous compounds.

PROLINE DERIVATIVES AND RELATED COMPOUNDS

New proline derivatives and related compounds which have the general formula STR1 are useful as angiotensin converting enzyme inhibitors.