1192477-22-7

Basic information

• Product Name: (S)-6-amino-2-{cyclohexylmethyl-[2-(1H-indol-3-yl)-2-oxo-acetyl]amino}hexanoic acid
• Synonyms: (S)-6-amino-2-{cyclohexylmethyl-[2-(1H-indol-3-yl)-2-oxo-acetyl]amino}hexanoic acid
• CAS NO: 1192477-22-7
• Molecular Weight: 413.517
• Mol File: 1192477-22-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-6-amino-2-{cyclohexylmethyl-[2-(1H-indol-3-yl)-2-oxo-acetyl]amino}hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-6-amino-2-{cyclohexylmethyl-[2-(1H-indol-3-yl)-2-oxo-acetyl]amino}hexanoic acid(1192477-22-7)
• EPA Substance Registry System: (S)-6-amino-2-{cyclohexylmethyl-[2-(1H-indol-3-yl)-2-oxo-acetyl]amino}hexanoic acid(1192477-22-7)

Safety Data

• Hazardous Substances Data: 1192477-22-7(Hazardous Substances Data)

Upstream product

• 22980-09-2 indolyl-3-glyoxylyl chloride 
• 13288-57-8 1,1-dimethylethyl N₆-{[(1,1-dimethylethyl)oxy]carbonyl}-L-lysinate hydrochloride 
• 2043-61-0 cyclohexanecarbaldehyde 

Relevant articles and documents

CALCIUM ION CHANNEL MODULATORS and USES THEREOF

Compounds of formula (I), wherein R1 is hydrogen, hydroxyl or aralkyl; R2 is an optionally substituted alkyl, aryl or heteroaryl (said substituents are selected from hydroxyl, alkoxyl, haloalkoxyl, aryl, heteroaryl, cycloalkyl, amino, monoalkylamino, dialkylamino, alkylsulphonyl, alkylsulphinyl, alkylsulphonylamino, acylamino, saturated or partially unsaturated heterocyclic groups and groups of formula COY); W is selected from oxygen, sulphur, groups of formula NR7, wherein R7 is hydrogen, alkyl, aryl or heteroaryl and groups of formula CR8R9, wherein R8 and R9 are hydrogen, alkyl, aryl or heteroaryl; and X is selected from nitrogen and groups of formula CR10, wherein R10 is hydrogen, alkyl, aryl, heteroaryl, halogen or haloalkyl, inhibit the interaction between Cavx channels and Cavβ proteins and are of use in the treatment and prevention of a number of diseases and conditions including pain and lower urinary tract disorders.