119249-25-1Relevant academic research and scientific papers
Synthesis and some reactions of 7-methylcoumarin-4-acetic acid
Soliman, A Y,El-Kafrawy, A F,Mohamed, F K,Baker, H M,Abdel-Gawad, A M
, p. 477 - 481 (2007/10/02)
7-Methylcoumarin-4-acetic acid (1) has been prepared and condensed with aromatic aldehydes to give the corresponding 4-(2-arylethenyl)-7-methyl-2H-1-benzopyran-2-ones (IIa,b).The cycloaddition of IIa,b with maleic anhydride gives the corresponding Diels-Alder adducts (IIIa,b) and (IV).Action of primary amines or hydrazines on III affords the corresponding N-alkyl/N-aryl derivatives (Va-h) and benzopyrano phthalazinetriones (VIa-d), respectively.Reaction of IIIa with aromatic and aliphatic hydrocarbons under Friedel-Crafts conditions gives 7-(aryl-or alkyl-carbonyl) derivatives (VIII).
