1192707-07-5

Upstream product

• 16982-21-1 ethyl 2-amino-2-thioxoacetate 
• 34969-79-4 2-bromo-1-(3,5-dibromo-4-hydroxyphenyl)ethanone 

Downstream Products

• 1192706-89-0 (4-benzylpiperidin-1-yl)(4-(3,5-dibromo-4-hydroxyphenyl)thiazol-2-yl)methanone 
• 1192707-08-6 4-(3,5-dibromo-4-hydroxy-phenyl)-thiazole-2-carboxylic acid 

Relevant academic research and scientific papers

Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives

The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-14 or encompassed by formulas I-XII) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.

COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING THIAZOLE DERIVATIVES

The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in n