119271-78-2

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Basic information

Product Name: (+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride
Synonyms: Sezolamide hydrochloride; MK-417; (4S)-4-[(2-methylpropyl)amino]-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride (1:1)
CAS NO:119271-78-2
Molecular Formula: C₁₁H₁₉ClN₂O₄S₃
Molecular Weight: 374.9276
EINECS: N/A
Product Categories: N/A
Mol File: 119271-78-2.mol
Article Data: 2

Chemical Properties

Melting Point: N/A
Boiling Point: 580.5°C at 760 mmHg
Flash Point: 304.9°C
Appearance: N/A
Density: N/A
Vapor Pressure: 1.81E-13mmHg at 25°C
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride(CAS DataBase Reference)
NIST Chemistry Reference: (+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride(119271-78-2)
EPA Substance Registry System: (+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride(119271-78-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 119271-78-2(Hazardous Substances Data)

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119271-78-2 Usage

General Description

(+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride is a chemical compound that is used as a pharmaceutical drug. It belongs to the class of sulfonamides and is commonly used as an antihypertensive agent. (+)-(S)-4-(2-Methylpropylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride works by blocking certain receptors in the body, leading to vasodilation and decreased blood pressure. It is typically administered orally in the form of tablets or capsules and is often prescribed for the treatment of hypertension and heart failure. The hydrochloride salt form of this compound is more stable and provides better solubility, making it suitable for use in pharmaceutical formulations.

Check Digit Verification of cas no

The CAS Registry Mumber 119271-78-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,2,7 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 119271-78:
(8*1)+(7*1)+(6*9)+(5*2)+(4*7)+(3*1)+(2*7)+(1*8)=132
132 % 10 = 2
So 119271-78-2 is a valid CAS Registry Number.

119271-78-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	(4S)-4-(2-methylpropylamino)-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide,hydrochloride

1.2 Other means of identification

Product number	-
Other names	SEZOLAMIDE HYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119271-78-2 SDS

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119271-78-2Relevant articles and documents

Thienothiopyran-2-sulfonamides: Novel topically active carbonic anhydrase inhibitors for the treatment of glaucoma

Baldwin,Ponticello,Anderson,Christy,Murcko,Randall,Schwam,Sugrue,Springer,Gautheron,Grove,Mallorga,Viader,McKeever,Navia

, p. 2510 - 2513 (1989)

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