1192712-72-3Relevant academic research and scientific papers
Asymmetric Total Syntheses of the trans -2-Aryl-6-alkyltetrahydropyrans Diospongin B and Parvistones D and e from a Common Precursor
Li, Zhilong,Tong, Rongbiao
, p. 1630 - 1636 (2016)
Asymmetric total syntheses of diospongin B and parvistones D and E are reported. Our strategy features a high-yielding three-step reaction sequence: Achmatowicz rearrangement, reductive γ-deoxygenation, and Matsuda-Heck coupling to construct the rare and challenging trans-2-aryl-6-alkyltetrahydropyrans, which serve as common intermediates for the syntheses of diospongin B, and parvistones D and E.
A flexible enantioselective total synthesis of diospongins A and B and their enantiomers using catalytic hetero-diels-alder/Rh-catalyzed 1,4-addition and asymmetric transfer hydrogenation reactions as key steps
Kumaraswamy, Gullapalli,Ramakrishna, Gajula,Naresh, Police,Jagadeesh, Bharatam,Sridhar, Balasubramanian
supporting information; experimental part, p. 8468 - 8471 (2010/02/28)
(Chemical Equation Presented) A unified enantioselective route to total synthesis of diospongins A and B and their enantiomers has been developed employing achiral starting materials. All three stereocenters were introduced by means of catalytic reactions
